Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of a2ML1 in human serum, plasma, tissue homogenates.
Target Information: This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP\, PMID: 20805888). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]